In the bottom of the image, the bright cloud is a reflection nebula known as [B77] 63, a cloud of interstellar gas that is reflecting light from the stars embedded within it. These stars are lighting up the surrounding gas and sculpting it into the wispy shape seen in this image.
However, the most interesting part of this image is the dark stream of smoke piling outwards from [B77] 63 and its stars. Its a dark nebula called Dobashi 4173. Dark nebulae are incredibly dense clouds of pitch-dark material that obscure the patches of sky behind them, seemingly creating great rips and eerily empty chunks of sky.
article reference:- nasa.gov
Image Credit: ESA & NASA